Process of the week

Industrial Synthesis of molnupiravir (Merck)

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Jonathan Maturano

Oct 15, 2021

E2609 - BACE1 Inhibitor

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Chris Davis

Sep 3, 2021

BMS-986251

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Marko Nesic

Jun 26, 2021

Industrial Syntheses of BMT - 362265

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Roberto Serrano

Jun 12, 2021

Lithiation Towards AZD5718

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Peter Ryffel

May 8, 2021

AZD6738 (Ceralastertib)

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Annie Hooper

Apr 10, 2021

Nemiralisib (C-H Functionalization)

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Marko Nesic

Mar 14, 2021

One-Pot Synthesis of Nefopam HCl

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Jonathan Maturano

Feb 7, 2021

Uprifosbuvir (MK-3682)

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Maegen Kincanon

Jan 24, 2021

Selective Oxidation of Methane

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Chris Davis

Jan 10, 2021

ASP5069

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Tanner Bingham

Dec 5, 2020

Lanabecestat

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Daniel Szczepankiewicz

Nov 14, 2020

TV-45070

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Sungjong Lee

Oct 30, 2020

(2S)-2-Methyltetrahydropyran-4-one

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D.G. Dennis

Oct 16, 2020

LY2623091 - MR Antagonist

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Chris Davis

Oct 2, 2020

One-pot Process for Nalbuphine Hydrochloride

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Christopher J. Huck

Sep 11, 2020

Pharmacy on Demand

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Tanner Bingham

Aug 28, 2020

SN-38; Irinotecan

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Daniel Szczepankiewicz

Jul 31, 2020

Glucokinase Activator (TEIJIN)

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Marko Nesic

Jul 10, 2020

GDC-0022: a RORc Reverse Agonist

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Alexander S. Shved

Jun 12, 2020

Telaprevir (Incivek™, Incivo™)

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Daniel Szczepankiewicz

May 22, 2020

The Industrial Synthesis of (+)-Discodermolide

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Roberto Serrano

May 8, 2020

Dolutegravir Sodium (Tivicay)

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Maegen Kincanon

Apr 24, 2020

Carfilzomib Part 2:

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Matt Bock

Apr 10, 2020

Carfilzomib Part 1

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Zohaib Siddiqi

Apr 3, 2020

AZD9742

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Matt Bock

Mar 27, 2020

Enantioselective Alkynylation for GPR40 Agonist

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Yaroslav D. Boyko

Feb 19, 2020

MK-6096, a Dual Orexin Receptor Antagonist

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D. G. Dennis

Jan 24, 2020

Polymorphism in Ritonavir (Norvir®)

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Daniel Szczepankiewicz

Jan 10, 2020

A Dual BCl-2/Bcl-XL Agonist. Part 1.

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David G. Dennis

Dec 6, 2019

Rinskor Pt.II

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Zohaib Siddiqi

Nov 15, 2019

Omecamtiv Mecarbil

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Sungjong Lee

Oct 25, 2019

GZ/SAR402671

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Matt Bock

Oct 11, 2019

GDC-0276

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Marko Nesic

Sep 27, 2019

Tyclopyrazoflor

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Sungjong Lee

Aug 23, 2019

EGFR-T790M Inhibitor

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Matt Bock

Aug 2, 2019

GSK2248761A (IDX-899)

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Sungjong Lee

Apr 12, 2019

BI 665915

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Marko Nesic

Mar 1, 2019

K-8986

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Annie Hooper

Feb 8, 2019

TEV-37440

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Chad N. Ungarean

Jan 19, 2019

Advair Diskus

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David G. Dennis

Jan 4, 2019

Case Study of RG7834

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David G. Dennis

Oct 28, 2018

Hydrosilation briefing

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Chad N. Ungarean

Oct 12, 2018

Stereoselective Synthesis of ProTides

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Lucas W. Hernandez

Sep 28, 2018

MK-6096

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Emma H. Southgate

Sep 14, 2018

BMS-791325 (Beclabuvir)

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Tanner W. Bingham

Aug 24, 2018

Travoprost

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Alexander S. Shved

Aug 2, 2018

Solid-Liquid-Liquid-Gas Photochemical C-N Oxidation

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Maegen Kincanon

Oct 1, 2021

AZD4573

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Annie Hooper

Jul 31, 2021

Thianthrene Mediated C-H activation (Ritter)

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Zohaib Siddiqi

Jun 19, 2021

Prexasertib

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Amanda Milkovits

May 29, 2021

Scalable synthesis of (S)-3-Fluoromethyl-γ-butyrolactone

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David Ryffel

May 1, 2021

tacalcitol

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Zohaib Siddiqi

Mar 27, 2021

GSK1292263A and GSK2041706A

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Amanda Milkovits

Feb 14, 2021

Cabotegravir (GSK)

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Peter Ryffel

Jan 31, 2021

Scalable synthesis of [(DMPU)2Zn(CF2H)2]

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David Ryffel

Jan 17, 2021

C-O bond formation in BMS-986118

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David Ryffel

Dec 13, 2020

FXI Inhibitor

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Maegen Kincanon

Nov 21, 2020

Mevidalen

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Matt Bock

Nov 7, 2020

Gefapixant Citrate (MK-7264)

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Marko Nesic

Oct 23, 2020

Sotagliflozin (LX4211)

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Daniel Szczepankiewicz

Oct 9, 2020

EMA-401

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Annie Hooper

Sep 18, 2020

Route Design for AZD4635

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David Ryffel

Sep 4, 2020

LSZ102

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Maegen Kincanon

Aug 14, 2020

Lamivudine (3TC)

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Sungjong Lee

Jul 17, 2020

IID572

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Chris Davis

Jul 3, 2020

BMS-929075

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Annie Hooper

Jun 5, 2020

Ziritaxestat

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Tanner Bingham

May 15, 2020

(R)-Lacosamide

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D. G. Dennis

May 1, 2020

UCB-108770

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David Ryffel

Apr 17, 2020

(S)-Ketamine (Esketamine)

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Jan Petrovcic

Apr 10, 2020

Edoxaban

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Chris Davis

Mar 27, 2020

Process Scale Ring-Closing Metathesis: Glecaprevir

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Chris Davis

Feb 28, 2020

LY3202626 — BACE1 Inhibitor

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David Ryffel

Feb 6, 2020

PF-06651600

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Maegen Kincanon

Jan 17, 2020

Islatravir

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Yaroslav D. Boyko

Dec 13, 2019

ASP3627

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Daniel Szczepankiewicz

Nov 22, 2019

Linrodostat (BMS986205)

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Chad N. Ungarean

Nov 8, 2019

Rinskor

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Zohaib Siddiqi

Oct 18, 2019

ABBV-3221

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Annie Hooper

Oct 4, 2019

Trans-3-Fluoro-4-Aminopyrrolidine

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Tanner Bingham

Sep 20, 2019

Asymmetric Nitrone-Olefin Cycloaddition

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Alexander S. Shved

Aug 16, 2019

Enantioselective Hayashi Addition in Recent API Synthesis

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Lucas Hernandez

Jul 19, 2019

Ghrelin Receptor Agonist (2243167-93-1)

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Daniel Szczepankiewicz

Mar 15, 2019

Ellman's auxiliary

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Tanner Bingham

Feb 15, 2019

BMS-978587

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Daniel Szczepankiewicz

Jan 25, 2019

PF-06650833

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Matt Bock

Jan 11, 2019

IPI-926 Cyclopropanation

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Emma Southgate

Nov 30, 2018

TPGS-750-M/H2O in organic synthesis

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Bowie Yi

Oct 19, 2018

Flow Chemistry in Multi-Step Fine Chemical Synthesis

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Mikiko Okumura

Oct 5, 2018

Asymmetric Alkylation of Trifluoromethyl Ketones

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Christopher J. Huck

Sep 21, 2018

Synthesis of tetrasubstituted olefins

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Uros Todorovic

Sep 7, 2018

GDC-0853

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Christopher Y. Bemis

Aug 17, 2018

Generation of nitroalkanes in a PFA pipe-in-series reactor

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Bowie Yi

Jul 20, 2018

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