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Process of the week
Process Development of a Topical Trk Inhibitor
Bobby Gilbert
Nov 17, 2024
GDC-9918 (Genentech)
Eric Pettipiece
Oct 12, 2024
Pilot Plant Synthesis of an HCV Protease Inhibitor
Yiannakis Lysandrou
Sep 7, 2024
Mutant IDH1 Inhibitor (Merck)
Eric Pettipiece
Jun 8, 2024
PF-07265807 (ARRY-067)
Bobby Gilbert
Apr 27, 2024
MRTX1719
Emma Simmons
Mar 16, 2024
GPR40 Agonist I
Kayla Landers
Jan 21, 2024
Nirmatrelvir (Pfizer)
Sam Barlock
Dec 10, 2023
ACT-777991 Fragment
Yiannakis Lysandrou
Oct 7, 2023
EBL-3183
Cheng Yang
Sep 5, 2023
Seltorexant (Janssen)
Jonathan Maturano
Jul 29, 2023
PF-07059013
Jingyang Zhang
Jun 24, 2023
Muscarinic antagonist for COPD (GSK)
Yiannakis Lysandrou
May 20, 2023
Lufotrelvir (PF-07304814)
Emma Simmons
Mar 25, 2023
BMS-644950: A Next-Generation Statin
Chris Davis
Feb 12, 2023
GSK3839919A
Kaio Gomes
Jan 15, 2023
ABBV-3748
Jan Petrovcic
Oct 1, 2022
MK-1029
Tsukasa Shimakawa
Sep 3, 2022
Omarigliptin
Chris Davis
Jul 23, 2022
BMS-986378 (CC-90010)
Jingyang Zhang
May 28, 2022
Optimization of the Synthesis of BMS-963272
Peter Ryffel
Apr 9, 2022
Branebrutinib (BMS-986195)
Annie Hooper
Mar 13, 2022
Odalasvir
Marko Nesic
Jan 30, 2022
Process Route to Simmerafil
Peter Ryffel
Oct 29, 2021
Solid-Liquid-Liquid-Gas Photochemical C-N Oxidation
Maegen Kincanon
Oct 1, 2021
AZD4573
Annie Hooper
Jul 31, 2021
Thianthrene Mediated C-H activation (Ritter)
Zohaib Siddiqi
Jun 19, 2021
Prexasertib
Amanda Milkovits
May 29, 2021
Scalable synthesis of (S)-3-Fluoromethyl-γ-butyrolactone
David Ryffel
May 1, 2021
tacalcitol
Zohaib Siddiqi
Mar 27, 2021
GSK1292263A and GSK2041706A
Amanda Milkovits
Feb 14, 2021
Cabotegravir (GSK)
Peter Ryffel
Jan 31, 2021
Scalable synthesis of [(DMPU)2Zn(CF2H)2]
David Ryffel
Jan 17, 2021
C-O bond formation in BMS-986118
David Ryffel
Dec 13, 2020
FXI Inhibitor
Maegen Kincanon
Nov 21, 2020
Mevidalen
Matt Bock
Nov 7, 2020
Gefapixant Citrate (MK-7264)
Marko Nesic
Oct 23, 2020
Sotagliflozin (LX4211)
Daniel Szczepankiewicz
Oct 9, 2020
EMA-401
Annie Hooper
Sep 18, 2020
Route Design for AZD4635
David Ryffel
Sep 4, 2020
LSZ102
Maegen Kincanon
Aug 14, 2020
Lamivudine (3TC)
Sungjong Lee
Jul 17, 2020
IID572
Chris Davis
Jul 3, 2020
BMS-929075
Annie Hooper
Jun 5, 2020
Ziritaxestat
Tanner Bingham
May 15, 2020
(R)-Lacosamide
D. G. Dennis
May 1, 2020
UCB-108770
David Ryffel
Apr 17, 2020
Carfilzomib Part 2:
Matt Bock
Apr 10, 2020
Edoxaban
Chris Davis
Mar 27, 2020
Process Scale Ring-Closing Metathesis: Glecaprevir
Chris Davis
Feb 28, 2020
LY3202626 — BACE1 Inhibitor
David Ryffel
Feb 6, 2020
PF-06651600
Maegen Kincanon
Jan 17, 2020
Islatravir
Yaroslav D. Boyko
Dec 13, 2019
ASP3627
Daniel Szczepankiewicz
Nov 22, 2019
Linrodostat (BMS986205)
Chad N. Ungarean
Nov 8, 2019
Rinskor
Zohaib Siddiqi
Oct 18, 2019
ABBV-3221
Annie Hooper
Oct 4, 2019
Trans-3-Fluoro-4-Aminopyrrolidine
Tanner Bingham
Sep 20, 2019
Asymmetric Nitrone-Olefin Cycloaddition
Alexander S. Shved
Aug 16, 2019
Enantioselective Hayashi Addition in Recent API Synthesis
Lucas Hernandez
Jul 19, 2019
Ghrelin Receptor Agonist (2243167-93-1)
Daniel Szczepankiewicz
Mar 15, 2019
Ellman's auxiliary
Tanner Bingham
Feb 15, 2019
BMS-978587
Daniel Szczepankiewicz
Jan 25, 2019
PF-06650833
Matt Bock
Jan 11, 2019
IPI-926 Cyclopropanation
Emma Southgate
Nov 30, 2018
TPGS-750-M/H2O in organic synthesis
Bowie Yi
Oct 19, 2018
Flow Chemistry in Multi-Step Fine Chemical Synthesis
Mikiko Okumura
Oct 5, 2018
Asymmetric Alkylation of Trifluoromethyl Ketones
Christopher J. Huck
Sep 21, 2018
Synthesis of tetrasubstituted olefins
Uros Todorovic
Sep 7, 2018
GDC-0853
Christopher Y. Bemis
Aug 17, 2018
Generation of nitroalkanes in a PFA pipe-in-series reactor
Bowie Yi
Jul 20, 2018
BI 1147560 BS
Chien-Yi Chen
Nov 2, 2024
TP-2758
Emma Simmons
Sep 21, 2024
Adagrasib (MRTX849)
Kayla Landers
Aug 3, 2024
DNDI-6148
Zhaochen Duan
May 15, 2024
Baloxavir Marboxil (BXM)
Chien-Yi Chen
Apr 13, 2024
Avibactam
Yiannakis Lysandrou
Mar 3, 2024
BI 1181181 MZ
Cheng Yang
Jan 7, 2024
Pyridoazepine Scaffold
Jan Petrovcic
Oct 21, 2023
JAK1 Inhibitor: AZD4604
Kayla Landers
Sep 23, 2023
Pyrimidinyl Cyclopropane Carboxylic Acid
Jan Petrovcic
Aug 26, 2023
Ensitrelvir
Tsukasa Shimakawa
Jul 8, 2023
MRTX0902 (Mirati Therapeutics)
David Ryffel
Jun 10, 2023
CD73 Inhibitor : AB680
Chein-Yi Chen
Apr 29, 2023
ARS-2102
Zhaochen Duan
Mar 12, 2023
Kilogram Scale Synthesis of YG-056SP
Peter Ryffel
Jan 29, 2023
PIK3γ Inhibitor – Arcus Biosciences
David Ryffel
Oct 29, 2022
Uprifosbuvir (MK-3682)
Annie Hooper
Sep 17, 2022
MK-1454
Marko Nesic
Aug 20, 2022
Pyrrolidine Fragment of Upadactinib
Matteo Martinelli
Jul 9, 2022
Kilogram-Scale Route for Cipepofol
Jonathan Maturano
Apr 30, 2022
Tubulysin Core
Matteo Martinelli
Mar 26, 2022
GSK2838232
David Ryffel
Feb 13, 2022
BRD5018 - Antimalarial Agent
Chris Davis
Jan 11, 2022
Industrial Synthesis of molnupiravir (Merck)
Jonathan Maturano
Oct 15, 2021
E2609 - BACE1 Inhibitor
Chris Davis
Sep 3, 2021
BMS-986251
Marko Nesic
Jun 26, 2021
Industrial Syntheses of BMT - 362265
Roberto Serrano
Jun 12, 2021
Lithiation Towards AZD5718
Peter Ryffel
May 8, 2021
AZD6738 (Ceralastertib)
Annie Hooper
Apr 10, 2021
Nemiralisib (C-H Functionalization)
Marko Nesic
Mar 14, 2021
One-Pot Synthesis of Nefopam HCl
Jonathan Maturano
Feb 7, 2021
Uprifosbuvir (MK-3682)
Maegen Kincanon
Jan 24, 2021
Selective Oxidation of Methane
Chris Davis
Jan 10, 2021
ASP5069
Tanner Bingham
Dec 5, 2020
Lanabecestat
Daniel Szczepankiewicz
Nov 14, 2020
TV-45070
Sungjong Lee
Oct 30, 2020
(2S)-2-Methyltetrahydropyran-4-one
D.G. Dennis
Oct 16, 2020
LY2623091 - MR Antagonist
Chris Davis
Oct 2, 2020
One-pot Process for Nalbuphine Hydrochloride
Christopher J. Huck
Sep 11, 2020
Pharmacy on Demand
Tanner Bingham
Aug 28, 2020
SN-38; Irinotecan
Daniel Szczepankiewicz
Jul 31, 2020
Glucokinase Activator (TEIJIN)
Marko Nesic
Jul 10, 2020
GDC-0022: a RORc Reverse Agonist
Alexander S. Shved
Jun 12, 2020
Telaprevir (Incivek™, Incivo™)
Daniel Szczepankiewicz
May 22, 2020
The Industrial Synthesis of (+)-Discodermolide
Roberto Serrano
May 8, 2020
Dolutegravir Sodium (Tivicay)
Maegen Kincanon
Apr 24, 2020
(S)-Ketamine (Esketamine)
Jan Petrovcic
Apr 10, 2020
Carfilzomib Part 1
Zohaib Siddiqi
Apr 3, 2020
AZD9742
Matt Bock
Mar 27, 2020
Enantioselective Alkynylation for GPR40 Agonist
Yaroslav D. Boyko
Feb 19, 2020
MK-6096, a Dual Orexin Receptor Antagonist
D. G. Dennis
Jan 24, 2020
Polymorphism in Ritonavir (Norvir®)
Daniel Szczepankiewicz
Jan 10, 2020
A Dual BCl-2/Bcl-XL Agonist. Part 1.
David G. Dennis
Dec 6, 2019
Rinskor Pt.II
Zohaib Siddiqi
Nov 15, 2019
Omecamtiv Mecarbil
Sungjong Lee
Oct 25, 2019
GZ/SAR402671
Matt Bock
Oct 11, 2019
GDC-0276
Marko Nesic
Sep 27, 2019
Tyclopyrazoflor
Sungjong Lee
Aug 23, 2019
EGFR-T790M Inhibitor
Matt Bock
Aug 2, 2019
GSK2248761A (IDX-899)
Sungjong Lee
Apr 12, 2019
BI 665915
Marko Nesic
Mar 1, 2019
K-8986
Annie Hooper
Feb 8, 2019
TEV-37440
Chad N. Ungarean
Jan 19, 2019
Advair Diskus
David G. Dennis
Jan 4, 2019
Case Study of RG7834
David G. Dennis
Oct 28, 2018
Hydrosilation briefing
Chad N. Ungarean
Oct 12, 2018
Stereoselective Synthesis of ProTides
Lucas W. Hernandez
Sep 28, 2018
MK-6096
Emma H. Southgate
Sep 14, 2018
BMS-791325 (Beclabuvir)
Tanner W. Bingham
Aug 24, 2018
Travoprost
Alexander S. Shved
Aug 2, 2018
Archive
Name | Title | Date |
|---|---|---|
Christopher Bemis | Pfizer Pyrrolospiropiperidine Process | 11/02/2018 |
Chad Ungarean | DMP 323 and 450 (Mozenavir) | 07/13/2018 |
William Wertjes | BMS-986163 | 07/06/2018 |
David Dennis | Preparation of a Lead Antibacterial Macrolone Compound | 06/22/2018 |
Tanner Bingham | Cephalosporin Drugs | 06/09/2016 |
Conghui Tang | BMS-663068 (Part 9) | 01/10/2018 |
Petra Galer | BMS-663068 (Part 8) | 01/05/2018 |
Bowie Yi | BMS-663068 (Part 7) | 12/08/2017 |
Yaroslav D. Boyko | BMS-663068 (Part 5) | 11/17/2017 |
David G. Dennnis | BMS-663068 (Part 4) | 11/10/2017 |
Mikiko Okumura | BMS-663068 (Part 3) | 11/03/2017 |
David G. Dennnis | BMS-663068 (Part 2) | 10/27/2017 |
Tanner W. Bingham | BMS-663068 (Part 1) | 10/20/2017 |
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